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COVID-19

Europe’s vaccine woes deepen as regulator probes another jab over blood clot concerns

Europe's stuttering vaccine rollout faced multiple hurdles on Friday as EU regulators said they were reviewing side effects of the Johnson & Johnson shot and France further limited its use of the AstraZeneca jab.

Europe's vaccine woes deepen as regulator probes another jab over blood clot concerns
Syringes for the single dose Johnson & Johnson vaccine. credit: FREDERIC J. BROWN / AFP

The US drugs regulator said it had not found a “causal” link between the J&J vaccine and blood clots, but that its probe was continuing after “a few individuals” suffered complications.

Much of the world is still in the clutches of the pandemic that has killed 2.9 million people, from Brazil, where the virus is killing more than 4,000 people a day, to Japan where the government has tightened restrictions once again.

In India, the worst-hit state of Maharashtra is running out of vaccines as the health system buckles under the weight of the contagion. Home to megacity Mumbai, Maharashtra has been placed under a curfew and weekend lockdowns.

And across Europe populations are facing some of the world’s toughest anti-virus measures, yet the epidemic refuses to be curbed.

All of France is subjected to restrictions of some form, and the country has so far doled out jabs to more than 10 million people.

But it has repeatedly changed the rules on AstraZeneca’s vaccine, first over doubts about its efficacy, then over fears that it could be linked to blood clots.

SEE ALSO: How fast is France vaccinating its population compared to other European countries?

On Friday it did so again, with Health Minister Olivier Veran saying citizens under 55 who had been given a first shot with AstraZeneca would be given a different vaccine for their second dose.

But shortly after he spoke, the World Health Organization said there was “no adequate data” to support switching Covid-19 vaccines between doses.

‘One more day’

As Europe continues to reel from constant rows over AstraZeneca’s jab, the EU’s medicine regulator announced it would be probing a second jab over bloodclot concerns.

The European Medicines Agency (EMA) said four “serious cases” of unusual blood clots had been reported — one of them fatal — with the Johnson & Johnson vaccine, which uses similar technology to the AstraZeneca one.

The US Food and Drug Administration said it had found no “causal” link yet between the jab and clots.

But it noted “a few individuals” in the country had clots and low levels of platelets in the blood after receiving the vaccine, and its investigation was continuing.

“Both conditions can have many different causes,” the agency said.

Johnson & Johnson released a statement saying the company was aware that “thromboembolic events… have been reported with all Covid-19 vaccines”.

But the statement added: “At present, no clear causal relationship has been established between these rare events and the Janssen COVID-19 vaccine,” referring to J&J’s European subsidiary.

Both jabs are approved for use in the European Union but the J&J vaccine has not yet been rolled out, and various EU countries have stopped or limited the use of AstraZeneca.

Supply problems

Supply problems are also hampering vaccine rollouts.

India, which is one of the world’s leading manufacturers of vaccines, is suffering its own problems with jabs in Maharashtra, home to more than 100 million people and the economic hub Mumbai.

“Most hospitals in Mumbai will exhaust their supplies by the end of the day,” Mangala Gomare, who oversees the city’s vaccination programme, told AFP Friday.

In the United States, deliveries of the Johnson & Johnson vaccine are set to drop off sharply next week, US health authorities warned Friday.

Meanwhile Pfizer-BioNTech asked for authorisation to use their Covid-19 vaccine on 12-15 year olds in the US.

The companies said in a statement that they plan to make similar requests of other regulatory authorities worldwide in coming days.

In Europe, an AstraZeneca spokesman said half of its vaccine shipments to the EU will be delayed this week.

Swedish climate campaigner Greta Thunberg said Friday she would skip a forthcoming climate meeting in Britain because countries were unable to participate on even terms.

READ MORE: Swedish region makes U-turn on new Covid-19 vaccination rules

“With the extremely inequitable vaccine distribution I will not attend the COP26 conference if the development continues as it is now,” Thunberg told AFP.

Illustrating her point, Britain has so far given at least one jab to more than 31 million people, almost half of its population, compared with poorer countries like Mexico, which has administered fewer than 10 million jabs to only seven percent of its people.

‘Everyone is not equal’

Germany’s central government has tried hard to defeat the virus through restrictions on movement and commerce, but several states have torpedoed the strategy by refusing to go along with the proposals.

Now Berlin is changing the rules to gather more centralised power.

READ MORE: Germany to tighten national coronavirus law in bid to ‘create uniform rules’

The proposed adjustments are likely to usher in night-time curfews and some school closures in especially hard-hit areas.

Japan has also tightened measures in the capital Tokyo and other areas, mostly calling for bars to close early.

On the other hand, Italy is set to end lockdown measures from next week for Lombardy, the epicentre of its coronavirus pandemic, and several other regions with improving contagion statistics.

Neighbouring Slovenia also announced it will ease coronavirus restrictions and suspend a six-month-long curfew starting Monday.

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COVID-19

What you need to know about the new Covid-19 wave in Switzerland

When the pandemic was winding down two years ago, health authorities warned that while the worst was over, Covid will keep re-emerging, in one form or another, in the future.

What you need to know about the new Covid-19 wave in Switzerland

In Switzerland, the number of laboratory-confirmed coronavirus cases has increased by around 50 percent over the last four weeks, according to the Federal Office of Public Health (FOPH).  

Add to it the undeclared cases, and that figure is even higher.

“The number of positive tests is climbing, and further increases cannot be ruled out,” FOPH said.

Overall, however, the number of infections remains low.

Why is Covid still around in Switzerland?

As epidemiologists predicted, coronavirus will keep mutating, with different strains emerging over time.

Covid’s new variants, KP.2 and KP.3, are currently circulating throughout the country, causing the number of cases to go up.

That’s because the latest variants spread fast and are particularly resistant to antibodies — which means that whatever immunity you may have built up through previous infections or vaccinations are not sufficient to stop new infections.

What are the symptoms?

The most common ones are similar to those of seasonal flu — that is, cough, fever, headache, muscle pain, cold, sore throat, as well as tiredness.

But just as with the previous bouts, some people will experience milder symptoms, while others more severe ones.

For the time being, these variants have not caused serious developments in most people, and only a small number have required hospitalisation.

What should you do if symptoms appear?

If you do become infected, FOPH recommends avoiding contact with other people, especially those who are particularly at risk of complications.

Measures imposed by the government during earlier outbreaks, such as isolation and quarantine, are not necessary at this point — though health authorities say that, similarly to to previous bouts, you should wear a mask and keep your distance.

And if you are in a high-risk group, contact your doctor immediately.

Should you get (re)vaccinated?

Ask your doctor about that.

Compulsory basic insurance will pay for the vaccine for high-risk people, and possibly their carertakers, based on doctor’s recommendations.

Others must pay for the shot out of their pockets. A dose costs around 100 francs.

Should you cancel your vacation if you test positive?

It is up to you and your own sense of responsibility.

“It would be best to cancel the flight immediately,” said Christiane Meier, vice-president of the Association of Cantonal Doctors. If you decide to go anyway, “wear a mask and keep your distance,” she added.
 
Should we expect a further increase in the number of cases after the holidays?

According to FOPH, it is not yet possible to know for sure, though this possibility can’t be excluded.

Swiss health authorities are constantly monitoring the evolution, but are not making any predictions for the moment.

What they do say is that though new variants spread fast and resist immunity, “there is no reason to panic at this stage.”

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